Tissue Typing and Immunogenetics Unit

The Tissue Typing and Immunogenetics Unit is part of the Department of Clinical Microbiology and Infectious Diseases.  The Unit for tissue typing and matching provides immunogenetic evaluation for bone marrow transplantation, solid organ transplantation (kidney, pancreas, heart, lung and liver), differential diagnosis of various diseases, prenatal diagnosis of diseases relating to the tissue matching network, paternity, maternity and parentage testing and forensic medicine.

Laboratory Highlights

The Tissue Typing and Immunogenetics Unit performs tissue typing evaluation at the serological, molecular and cellular level.  Among the services offered are examination for the presence of  HLA antibodies, detection of mutations in CYP21B and mutation analysis of HLA for detection of diseases in linkage to HLA.

Since 70 percent of patients in need of bone marrow transplantation do not have an HLA matched donor, the Tissue Typing Unit has established an unrelated bone marrow donor registry and an umbilical cord blood bank and registry and is very active engaged in enlarging the number of unrelated donors in these registries.